In this episode of *Dr. Pepper...Really?*, we explore the intriguing world of anti-aging research and the unexpected star—metformin.  A mainstay of treatment for Type 2 diabetes, metformin is now showing potential as a powerful tool in extending healthspan and combating the effects of aging. Could a simple pill that costs less than a dollar actually hold the key to preserving youth?Recent groundbreaking research on monkeys reveals that metformin might slow age-related decline in the brain and organs, effectively "dialing back" biological age. The study shows improved cognitive function, reduced inflammation, and even the restoration of youthful health in multiple organs. This new chapter in metformin’s story is drawing attention from scientists and the general public alike, sparking new hopes for enhancing healthy aging.Join us as we discuss the science behind these promising findings and dive deep into how metformin might redefine our future. We also introduce a new conversational dialogue format enhanced by AI, designed to make the experience more engaging and enjoyable for you. Don’t miss this captivating journey through the latest in longevity science, where the old becomes new, and the future of aging may now be within our grasp.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Along with the amazing weight loss results with medications such as #Ozempic #Wegovy #Mounjaro and #Zepbound, comes the unwanted complication of malnutrition. Join Dr. Gary Pepper in an insightful discussion of this "in the news" metabolic health issue. Malnutrition associated with rapid weight loss can take the form of muscle wasting, generalized weakness, sagging skin and hair loss. Learn what a major consumer products company is planning in order to help aggressive dieters in their quest to stay healthy and lose weight at the same time.  Can you DIY this type of nutrient rich approach? Dr. Pepper offers some thoughtful suggestions for you. His accompanying YouTube video on this subject can be found at https://youtu.be/ka8OHHEOWVEGary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

The journey through menopause doesn't have to include weight gain as a constant companion. A new study unveils that estrogen replacement therapy may boost the effectiveness of weight loss medications like semaglutide. This synergy could be the missing link for many struggling with menopausal metabolism. However, the decision to use estrogen therapy is complex, with potential health risks that must be weighed against its metabolic advantages. Check out the full blog on this topic at our website metabolism.com, for more detailsGary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Listen in on the  latest episode of Dr. Pepper...Really. This interview features Kelly's  personal account of using GLP-1 agonist medications to combat menopause-induced weight gain. Kelly's experience offers a glimpse into the potential benefits and challenges of these drugs, including side effects and concerns about long-term use. Topics also include thoughts on whether teenagers should be taking these medication, and the problems with muscle loss associated with the GLP-1 class of drugs. Her story is an invaluable resource for those facing similar struggles. Additional blogs by Dr. Pepper appear on his website metabolism.com and the video versions on YouTube at his channel metabolism123Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Embark on an enthralling exploration of the adrenal gland, both an unsung hero or potential enemy nestled atop our kidneys, with this comprehensive and fascinating overview. Dr. Gary Pepper, an esteemed endocrinologist with 40 years of experience, demystifies the complex workings of this tiny titan responsible for our hormonal balance. From life-sustaining cortisol to the adrenaline that fuels our fight-or-flight response, discover the pivotal role these glands play in our well-being. This podcast also delves into the nuances of adrenal disorders, shedding light on conditions like adrenal insufficiency and the contentious 'adrenal fatigue,' offering a rich tapestry of insight into the elements that can undermine our health. Presented in a manner that is both captivating and educational, this podcast is an exceptional resource for anyone eager to understand the intricacies of endocrine health. Other sources of information prepared by Dr. Pepper include his YouTube channel metabolism123 and website www.metabolism.com. Consider visiting these other resources to access  exemplary content that bridges the gap between medical complexity and patient understanding, crafted by a true connoisseur of endocrinology.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Join renowned endocrinologist Gary Pepper, M.D. as he delves into the real-world experiences of individuals using Ozempic and Rybelsus for weight loss. In this exclusive interview with Ellen, hear her account of her experience with these potent medications.  With over 40 years of experience in the field, Dr. Pepper provides expert analysis and interpretation, offering invaluable insights for listeners considering similar treatments. Don't miss this opportunity to gain trustworthy information and stay informed about the latest developments in metabolic health. Keep watching for more from Dr. Pepper at his podcast Dr. Pepper...Really.  And don't forget to visit metabolism123 on YouTube and the website www. metabolism.com. Disclaimer: this podcast is for educational purposes only and is not intended to provide medical care or advice. Please consult with your own provider for your personal health care needs and concernsGary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Using the AI tool, the Metabolic Mentor at www.metabolism.com, Dr. Gary Pepper demonstrates his methods for searching for high quality health information. After 40 years as a practicing endocrinologist and 25 years as an internet pioneer, Dr. Pepper is highly qualified to provide guidance in what can be a surprisingly complex and confusing task.   In this first tutorial he asks the Mentor to provide information about a common metabolic disorder, Hashimoto's Thyroiditis. At the same time,  Dr Pepper's editorial comments provide much needed insight into the interpretation of the results provided by the AI agent. Viewers are encouraged to recommend subjects for upcoming tutorials on other metabolic issues, in the comment section of the video or by email to info@metabolism.com.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Join Dr. Gary Pepper, an esteemed endocrinologist with over four decades of expertise in patient care, research, and teaching, as he delves into the intricate relationship between weight loss, stress hormones, and their impact on our body in his latest podcast episode.In this enlightening discussion, Dr. Pepper begins by noting the unexpected connection between the use of weight loss medications like Ozempic and the occurrence of hair loss, prompting a deeper investigation into the hormonal responses triggered by rapid weight reduction. He sheds light on how our endocrine system, honed by evolution to protect us in times of scarcity, reacts to modern weight loss efforts by altering hormone levels, potentially affecting our hair, skin, nails, and overall body and mental function.Dr. Pepper elucidates the role of key hormones such as estrogen, testosterone, cortisol, and thyroid hormones, unraveling how they interplay with our body's physiological changes during weight loss. He also addresses the potential consequences of these hormonal shifts, including mood fluctuations, decreased metabolic rate, and even bone density concerns.Listeners will gain valuable insights into the body's natural preservation mechanisms and how they can inadvertently hinder our weight loss goals. Dr. Pepper advocates for a balanced approach to weight loss that avoids triggering the body's crisis response, emphasizing the importance of gradual weight reduction, proper nutrition, regular exercise, and adequate sleep.Whether you're a health enthusiast or someone navigating the journey of weight loss, Dr. Pepper's podcast offers a wealth of knowledge that underscores the importance of understanding our body's hormonal responses. Tune in to "Dr. Pepper Really" for a compelling session that not only informs but empowers you to take a more informed and healthier approach to weight loss.For additional information on this neglected aspect of healthy dieting visit Dr. Pepper's website Metabolism.com or view his video on this subject on YouTube.Disclaimer: Dr. Pepper's show and podcast channel present useful information but he does not warranty that some details of the presentations may be incomplete, erroneous or misrepresented.  This material is strictly for educational purposes only and does not replace the need for management of your health care by your personal health care provider. If you believe that information incorporated here needs to be changed you can contact Dr. Pepper...Really at info@metabolism.com.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

In this engaging follow-up episode, Susie enters  the 14th-week of her journey with Ozempic, highlighting its impact on her health and lifestyle. Initially hesitant about injections, she finds them surprisingly easy and experiences significant health improvements without major side effects, except for an isolated heartburn incident. Remarkably, Susie notes a shift in her eating habits, feeling full sooner and savoring food without overindulging. She's thrilled with a 14-pound weight loss and improved energy levels. Medical check-ups show encouraging results, particularly a notable decrease in her A1C levels, pushing her out of the diabetic range. Susie's commitment to a healthier lifestyle, including smarter food choices and ongoing medication, is evident. The podcast touches on broader issues of medication accessibility and the psychological aspects of weight loss, providing food for thought on this modern approach to an age-old challenge.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

The Dr. Pepper..Really Podcast.   Embark on a journey with Dr. Gary Pepper, a newly retired endocrinologist with 40 years of experience, as he demystifies Metformin, a drug hailed by many but not all  as a miracle in the diabetes community . From its historical roots to modern-day benefits and misconceptions, Dr. Pepper unravels the science behind Metformin's efficacy, side effects, and cost-effectiveness. This insightful podcast is a must for anyone curious about or managing type 2 diabetes, offering clear, accessible knowledge backed by decades of clinical and research expertise. Dive into this engaging exploration to understand why Metformin might just be the most valuable ally in your health arsenal.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Susie Starts Ozempic: An up close look at how a health professional starts her weight loss journeyJoin Dr. Gary Pepper, a seasoned endocrinologist, as he delves into the compelling story of Susie, a nurse practitioner who has grappled with weight issues for years. This intimate interview uncovers Susie's roller-coaster experience with various weight loss methods, from point-based food scoring to home-delivered meal plans, only to find herself in a recurring cycle of weight loss and regain.In this episode, we explore Susie's latest endeavor with Ozempic, a GLP-1 agonist that has been making waves on social media for its remarkable weight loss results. While not originally intended for weight loss, Ozempic's off-label use raises vital questions about its effectiveness, potential side effects, and the financial burden it brings.Dr. Pepper and Susie engage in a thought-provoking discussion on the pros and cons of this treatment, shedding light on the intricate balance between appetite suppression, the risk of side effects, and the looming possibility of rapid weight regain upon discontinuing the medication.As we anticipate Susie's progression to a higher dosage, stay tuned for our next segment where we will revisit her journey, exploring deeper into the efficacy and challenges of this treatment.This program, rich in educational insights, is not an endorsement or critique of any products or diets discussed. It serves as a reminder to consult with healthcare providers before embarking on any treatment program. Dive into this fascinating exploration of weight loss, medical treatments, and the personal struggles that accompany them.(Note: our channel Metabolism123 will be changing its name to Dr. Pepper...Really? in coming months)Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Over 40% of adults in the U.S. gained unwanted weight during the past 2 years of the pandemic. Stress eating appears to be a key reason for this phenomena.  In their 30 minute discussion the host Gary Pepper, M.D., endocrinologist and Robert Pepper, PhD, psychoanalyst cover the extent of weight gain during the pandemic (1:30), the psychologic reasons behind stress eating (3:18), how children joined the weight gain trend (4:50),  including the contribution of virtual learning (5:55), tactics for putting an end to unwanted weight gain (11:19), the contribution of alcohol consumption (13:25),  "connections are stronger than addictions" (18:01),  the benefits of family meals (21:01), exercise as therapy (23:24) and the role of denial in preventing personal progress (26:05).  Listeners can find more material on this topic  at the affiliated website www. metabolism.com This podcast is for educational purposes only and is not meant to provide medical treatment or advice. Listeners are encourage to consult with their own medical providers for advice on treatment for any and all medical conditions.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Episode 2. The Continuation of “Trouble in Paradise. The Obesity Epidemic”. The Dr. Pepper brothers, Drs Gary and Robert Pepper, continue their discussion of treating individuals who are overweight. Robert explains how in psychotherapy sessions he approaches the subject of being overweight with his clients and  emotional barriers preventing some people from talking about the issue. Later Robert delves into the types of unhealthy relationships people may have with body image and eating, and other unconscious hurdles that interfere with achieving their weight goals. Later Robert discusses attachments people form with food, for example, crunchy versus sweet, comfort foods etc. , that drive unhealthy eating. The two doctors compare notes on the challenges they face in their day to day interactions with treating overweight clients. Related information about this subject can be found at www.metabolism.comDisclaimer. The information and opinions expressed on the podcast Metabolism123 are for educational and entertainment purposes only. Only an individuals’ personal health care provider can prescribe treatment or diagnostic advice. Listeners agree to the terms and conditions found at the website www. metabolism.comGary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.

Dr. Gary Pepper,  a board certified endocrinologist is joined by his brother Dr. Robert Pepper, a psychotherapist for a discussion of the psychology of obesity. The discussion is geared to the general listener and does not require a medical background to be appreciated. This episode of metabolism123 begins with the therapist explaining how obese individuals confront or avoid the issue of overweight in their treatment sessions. Then the two Dr. Peppers share their insights and experiences with treating obesity acquired in their respective specialties.  Visit metabolism.com for transcripts of this podcast and to explore an extensive library of original articles on metabolism, thyroid disease, nutrition and many more related topics .Dr. Robert Pepper maintains his own website at DrRobertSPepperPhD.com where his contact information can be obtained.Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.